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英语词组“come up against”的意思是“遇到（困难、障碍等）”，读音为：“kəmˈʌp əˈfɔːnt”。这个词组通常表示在某件事情上遇到阻碍或挑战，尤其是在处理困难或复杂问题时。
例句：
1. When we tried to expand our business overseas, we came up against a language barrier. 我们试图把生意扩展到海外时，遇到了语言障碍。
2. The proposal we put forward was met with strong opposition, and we came up against a brick wall. 我们提出的建议遭到了强烈反对，我们遇到了阻碍。
3. He tried to solve the problem on his own, but eventually he came up against a wall. 他试图自己解决这个问题，但最终遇到了难题。
4. The lawsuits filed by competitors are making it difficult for us to come up with a plan for expansion. 竞争对手提出的诉讼使得我们很难为扩张计划找出路。
5. The financial constraints we are facing are forcing us to come up with creative solutions to overcome our challenges. 我们所面临的财务限制迫使我们想出创造性的解决方案来克服挑战。
6. When we started this new project, we didn't expect to come up against so many unexpected obstacles. 当我们开始这个新项目时，我们没想到会遇到这么多的意料之外的障碍。
7. The new regulations are going to come up against fierce opposition from some sectors of the industry. 新规定将会遭到行业内一些部门的激烈反对。
8. Even after exhaustive research, I still came up against the challenge of convincing potential clients of our competency. 尽管我进行了深入研究，我还是面临着一项挑战：如何让潜在客户相信我们是有能力胜任工作的。
9. Sometimes when things aren't going the way we planned, it's easy to feel like we're coming up against a brick wall. 有时事情不会按我们的计划发展，这时我们会很容易感到无助，觉得就像遇到了一堵无路可走的砖墙。
10. I think you'll find that most problems are easier to solve than you first imagined, once you start actively seeking solutions and don't give up when you come up against them. 一旦你开始积极地寻求解决方案并且面对困难时你不放弃，你会发现大多数问题比你原来想象的更容易解决。
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